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In individuals addicted to cocaine, reduced GLP-1 levels following cocaine injection are associated with increased cocaine intake and anxiety, while exenatide-4 supplementation decreases cocaine-induced preference and dopamine release

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However, it is important to be aware of the effect of the organosulfur solvent (DMSO) on the processes studied, even more so when a significant level of the solvent has been used to keep the molecule in the solution

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