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Although the exact clinical significance in humans remains unclear, preclinical research has focused on three main areas
H., Afshar, H., Roohafza, H., & Adibi, P
Despite causing an increased susceptibility to OS, G6PD deficiency may also protect against CVD, since NADPH is an essential cofactor for enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA R), and G6PD deficiency or NADPH deficiency may restrain HMG-CoA R activity similarly to statins (Fig
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