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As the GP activity was previously studied only in tissues such as rat liver and placenta without optimization of substrata conditions [7], the selection of blood as the target compartment to study the effect of systemic peroxide levels has the advantage of investigating the compartment subjected to all the comprehensive effects of peroxide systemic accumulation
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Furthermore, the oil red O staining showed it could be observed lipid droplets in some sections of HUA mice heart (Supplementary Figure 4F)
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