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While there are no FDA-approved therapies targeting Lp(a) reduction, sufficient evidence supports ASO and siRNA therapies for specifically lowering Lp(a) concentrations (albeit still in early-stage trials)

Each sub-segment plays a pivotal role in expanding access to GLP-1 receptor agonists, thereby enhancing therapeutic outcomes for patients managing chronic conditions

Funding: The present study was partly supported by the Samuel Rahbar Diabetes and Drug Discovery Endowment, Arthur Riggs Diabetes & Metabolism Research Institute and innovation grant from the Wanek Family Project for Type 1 Diabetes at City of Hope

However, that does not automatically make retatrutide "illegal." Instead, it currently exists in a regulatory gray area