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Factors such as stress, sodium intake, hormonal changes, poor sleep, travel, and exercise can all cause temporary water retention

If reactions first appeared or significantly worsened at a specific dose level, discuss the following options with your healthcare provider: extended time at the current dose before escalating further, smaller escalation increments , pre-injection antihistamine protocol, or exploring whether the therapeutic goals can be achieved at a lower dose

However, this is a generalization, not a guarantee, as individual factors can still vary

This overlap sets the stage for the key question: How do GLP-1 medications (like semaglutide) interact with IBS symptoms