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Chondrocyte dedifferentiation was majorly characterized as the reduced expression of COL2 and ACAN and enhanced expression of type I collagen and versican ( COL2 expression, but not ACAN ( In addition to dedifferentiation, another consequence of in vitro expansion is replicative senescence, which also significantly influences chondrocyte function

Impact of genetic variation of PPAR in humans

2.12 Shotgun metagenomic sequencing Fecal DNA ( n = 3/group) was extracted using a FastPure Stool DNA Isolation Kit (Magnetic Beads, MJYH, China), and its quality was assessed for concentration, purity, and integrity prior to fragmentation (400 bp) using a Covaris M220

Koushik Adhikari, a professor in the CAES department of food science and technology at the University of Georgia.