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The STEP trials and real-world data demonstrate that GLP-1 medications significantly reduce progression from prediabetes to type 2 diabetes, with some studies showing risk reduction of 70% or more

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The Science of Weight Regain and Why It Matters for Long-Term Planning One of the most clinically important findings to emerge from the GLP-1 and dual-agonist era is the magnitude of weight regain following discontinuation

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SC and oral formulations evaluated

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GLP1-RA users exhibited a significant risk reduction for anxiety, and a moderate reduction for depression, compared with non-users

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