UK and international guidance recognises that HbA1c has important limitations as a diagnostic and monitoring tool
Patients should seek emergency medical help (call 999) if they experience: Difficulty breathing, wheezing, or throat tightness Swelling of the face, lips, tongue, or throat (angioedema) Widespread urticarial rash (hives) developing rapidly Dizziness, fainting, or rapid heartbeat suggesting anaphylaxis These symptoms typically occur within minutes to hours of administration, most commonly with injectable preparations
For those with hematologic or renal risks, repeat testing at reasonable intervals (for example, after a few doses and then periodically) makes sense
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