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Studies show weight management outcomes vary depending on individual health factors, adherence to lifestyle recommendations, and treatment approach

BG-RRP-2.004-0009-C02 Special thanks to the Medical University-Varna and European Union for the financial support provided for the publication of the paper

Although excessive lipid accumulation, insulin resistance, and chronic low-grade inflammation are recognized as the main pathophysiological drivers, an increasing body of research indicates that the relationship between circadian rhythms, gut microbiota, and liver metabolism is far more complex than previously imagined, forming a systemic regulatory network

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