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Instruct patients to contact their healthcare provider if they have severe or persistent gastrointestinal symptoms [see Warnings and Precautions (5.7)] Hypersensitivity Reactions Inform patients that serious hypersensitivity reactions have been reported during postmarketing use of OZEMPIC

In total, the team examined 48 relevant studies, comprising 36 randomised controlled trials (RCTs) and 12 non-randomised studies

Nausea leads the list, affecting 40-44% of patients in clinical trials

Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat