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Compared to cytosolic NADK (cNADK), mitochondrial NADK (mNADK) has a distinctive feature that it can directly phosphorylate nicotinamide adenine dinucleotide (NADH) to generate NADPH to alleviate oxidative stress in mitochondria

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Raison et al., 2013), although it is unclear whether the improvement is due, at least in part, to their effects on the comorbid inflammatory diseases