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Orencia (abatacept) Disease area(s): Immunology Manufacturer(s): Bristol Myers Squibb 2024 Sales (USD): $3.68 billion Why it sold so well: Orencias global sales of $3.68 billion reflected a 2% increase compared to the previous year

There is a potential for more serious side effects, but they are rare

Overexpression of human IGF-I via direct rAAV-mediated gene transfer improves the early repair of articular cartilage defects in vivo

While some patients may self-administer after proper training, it is recommended that injections be performed by or under the guidance of healthcare professionals to ensure correct technique and dosing