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If improvement plateaus or symptoms persist despite treatment, further investigation may be warranted to identify other contributing factors or alternative diagnoses

[DOI] [PMC free article] [PubMed] [Google Scholar] [12].Black M, Trent A, Tirrell M

Vitamin B12 is not just another supplementit's a fundamental nutrient that touches nearly every aspect of your health, from cellular energy production to DNA synthesis and neurological function

In a pilot study of 32 migraine sufferers with insulin resistance, supplementation with 400 mg lipoic acid twice daily for six months significantly reduced the number of migraine attacks and days needing treatment, with improvements seen as early as two months (Cavestro 2018)