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This imaging approach has been successfully used for the original roGFP2 probe and different roGFP1-iX variants (Wierer et al., Generally, roGFP probes are appropriate for measuring the thiol/disulfide equilibrium within a linear range of about 30 mV from their midpoint potential equivalent to an OxD between 10 and 90%

Keeping track of any changes can help identify if the combination is causing any issues

Risk of lactic acidosis increases in patients with kidney disease, liver disease, or excessive alcohol use

in both study groups, the mean age was 65 years, 16% had higher education and 28% had a history of ischaemic heart disease (Table 1)