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The siP-Syn peptide (Chinapeptides, Shanghai, China) was injected via the tail vein every 3 days for 6 weeks at a dose of 10 mg/kg

For 96-well plates, 10 L of prepared reagent (1:50 ratio of monochlorobimane (MCB) to Tris assay buffer, per manufacturers instructions) was added to wells containing 100 L of culture media and incubated for 30 min at 37 C, washed with PBS, and imaged using an Olympus IX70 microscope with a DAPI filter (Excitation/Emission: 358 nm/461 nm)

Lipids are cell components that are most susceptible to oxidative modifications