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In Vitro Research In vitro cell culture studies using various cell types including myoblasts (muscle precursor cells), fibroblasts, and adipocytes demonstrated that IGF-1 DES produces DNA synthesis, cell proliferation, and metabolic responses at approximately one-tenth the concentration required for equivalent effects with full-length IGF-1, confirming the approximately 10-fold potency enhancement

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Two loci controlling synthesis of the glucose-repressible ADH II

Inhibits inflammation and oxidative stress, possibly acting as an antioxidant68