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Oncogene 25 , 16391648 (2006)

Sitagliptin, vildagliptin and saxagliptin did not alter innate immune response triggered by Toll-like receptor (TLR) activation in terms of secretion, co-stimulation, T cell proliferation and migration in human cells in vitro and in mice in vivo ( An initial meta-analysis reported that although DPP4i is not associated with an increased risk for respiratory infections they could increase the risk of urinary tract and nasopharyngitis infection (Pitocco et al., 2010), angioedema (Pitocco et al., 2020)