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Participants in this arm also showed improvements in waist circumference (a proxy for visceral fat), C-reactive protein (an inflammatory marker), and systolic blood pressure

Aim for: Regular walking or low impact cardio Strength training two or more days per week to preserve muscle Gentle activities such as yoga or Pilates to support stress management and mobility 5

If your tirzepatide-related headache persists or becomes severe, report it to your doctor immediately, as it may indicate an underlying issue or require a treatment adjustment

It is important to note that modifications in IGF-1 LR3 contribute to its low affinity to insulin-like growth factor binding proteins (IGFBP), extending its half-life