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The number of TEAEs was reported but was not specified as a study endpoint

For an insulin syringe (U-100 scale, 100 units = 1 mL): For published preclinical context: mouse studies (Billon 2023, PMID 37739806) used 25 mg/kg IP twice daily a much higher per-kilogram dose than community injectable users typically describe

Caking is the formation of permanent clumps due to the stickiness of particles which eventually can result in a loss of functionality and lowered quality [11, 12]

In conclusion, despite some limitations, our pilot study provides evidence that fibrosis induced by autologous DFb injection into degenerative IVDs can conserve IVD height, which in turn maintains the mechanical properties of the IVD