These include: Pre-existing constipation or slow transit constipation Inadequate dietary fibre intake Insufficient fluid consumption Reduced physical activity levels Concurrent medications with constipating effects (such as opioids, certain antidepressants, or iron supplements) Older age , where baseline colonic motility may already be reduced The severity of constipation often correlates with the dose of medication and may be more pronounced during dose escalation phases
My identity became Landon Donovan soccer player and not Landon the person
TIMPs, Tissue inhibitors of metalloproteinases
doi:[10.1111/dom.15728] Heather J Leidy, Peter M Clifton, Arne Astrup, Thomas P Wycherley, Margriet S Westerterp-Plantenga, Natalie D Luscombe-Marsh, Stephen C Woods, Richard D Mattes, The role of protein in weight loss and maintenance234, The American Journal of Clinical Nutrition, Volume 101, Issue 6, 2015, Pages 1320S-1329S,ISSN 0002-9165, Institute of Medicine