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Uncontrolled NSP activity contributes to lung damage in multiple acute and chronic inflammatory lung diseases, including acute lung injury, acute respiratory distress syndrome, chronic obstructive pulmonary disease (COPD), alpha-1 antitrypsin deficiency (AATD), bronchiectasis, and cystic fibrosis (CF) ( Figure 2) ( Figure 2 The requirement to maintain an adequate immune response to bacterial infection is a key consideration in developing treatments for neutrophil-mediated diseases

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Research published in Pharmacy and Therapeutics suggests patients with obesity can lose at least 5 percent of their body weight after using Contrave for 12 weeksand as much as 11.5 percent after 56 weeks

Less common side effects may include headache, dizziness, and allergic reactions such as rash or pruritus