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One real-world study found nearly half of the people who used an earlier generation of GLP-1 medication for diabetes quit within a year and 70% within two years.Meanwhile, about 4% of people in a clinical trial stopped taking Wegovy because of side effects

However, in reality, these two forms of treatment diverge greatly in their uptake, stability, clinical efficacy, and practical applicability

In recent years, its benefits for weight loss have gained attention, leading many to consider it as a potential aid in their weight loss endeavors

According to one report, prescriptions for semaglutide and tirzepatide together jumped by over 510% between late 2023 and mid-2025