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Tirzepatide does not directly cause frequent urination as a primary pharmacological effect

Research Insights Weight Loss and Obesity Management Clinical studies show that individuals treated with GLP-1 (S) experienced weight reductions of up to 15% over 68 weeks, significantly outperforming placebo groups ( 2, 3 )

this includes individuals who have multiple endocrine neoplasia syndrome type 2 (MEN2) or a personal or family history of medullary thyroid carcinoma (MTC)