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The beauty is in the selectivity: it triggers GH release without the cortisol spike or prolactin surge that some other peptides cause
GHRP-6 and GHRP-2, the earlier generation of GH secretagogues, activate not only GHS-R1a but also receptor systems involved in cortisol and prolactin release
The peptide was not reported to affect growth hormone pulse frequency or peak growth hormone levels
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