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A fifth mechanism is the potential association between parathyroid function and vitamin D receptor (VDR) polymorphism

Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor-beta2/insulin-like growth factor-1-mediated regulation of the hair cycle in male and female human hair follicles in vitro

The intervention yielded markedly significant enhancements in fatigue, diminished motivation, and anhedonia, alongside notable improvements in sleep disturbances, particularly those occurring in the middle of the night and early morning insomnia

This may impact overall longevity and well-being