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Glutathione and the glutathione peroxidase constitute the principal antioxidant defense system [25]

It reduces oxidative stress in the ovaries

In eight studies in which the effects of smoking cessation on endothelial function were assessed by biomarkers[19, 20, 23, 24, 30, 31, 92, 93], five studies showed that smoking cessation increased or improved biomarkers for endothelial function including circulating levels of nitrate/nitrite, NO, vvWF, ICAM-1, EPCs and EMPs and activity of eNOS [19, 23, 24, 30, 31]

Conclusion The current understanding of the PPP suggests a complex regulatory control of the PPP and a role of this pathway beyond the provision of NADPH