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At the same time, it promotes the differentiation of regulatory T cells, the very population that is dysfunctional in lupus

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* Correspondence: Wei Wei, [email protected] These authors share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Published preclinical research on FOXO4-DRI has demonstrated selective elimination of senescent cells in mouse models, with observed improvements in fitness markers, fur density, and organ function in aged subjects