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Clinical treatment strategy for MTHFR-related psychiatric disorders As MTHFR plays a critical role in one-carbon metabolism, which is composed of folate, homocysteine, vitamin B12, and methylation of DNA, mutation of specific gene locus on MTHFR and correlative enzyme activity decline will affect various of physiological events as well as some pathology states, including psychiatric disorders

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Counteract the damage caused by free radicals Reduced glutathione is an antioxidant that protects cells and organs by binding with free radicals in the body, then converts free radicals to acids substances that can be excreted

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