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Kidney transplantation and cystine-depleting therapy with oral and topical cysteamine have transformed cystinosis from a universally fatal childhood disorder into a treatable chronic disease, with many adults achieving normal lives

For patients exploring weight loss treatment options, understanding why combination therapy is not recommendedand what evidence-based alternatives existis essential for safe, effective care

Treat tirzepatide like a long-term medication, similar to a statin or blood pressure drug

To remove the variance in trait values attributed to sex and age differences, a linear regression model compared the retrieved residuals (adjusted trait values) using unpaired Students t test