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Fluid therapy is critical to improve hydration and blood flow to the pancreas (and other tissues) and to correct any electrolyte abnormalities

It activates the nitric oxide pathway, which regulates blood vessel formation and tissue perfusion

It is truncated analogue of growth hormone releasing hormone (GHRH), which was developed in 1980s from original GRF 1-29, but with purposefully prolonged half-life to ensure better therapeutical use

We agree that there would be inherently increased costs to hospitals for the new technology of a 365-day system, but we do not agree that the costs to hospitals would be almost double the costs of the 180-day system