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Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and mRNAs of NMDA receptor subunits in mouse models of depression

intense neuronal activity can deplete intracellular ATP, leading to K_ATP channel opening and a consequent reduction in firing, serving as a dynamic, activity-dependent brake on excessive excitation in the auditory brainstem (de Siqueira et al., 2025)

GIP (glucose-dependent insulinotropic polypeptide): Another gut hormone that directly enhances insulin sensitivity and adds another dimension of appetite regulation

The role of l-carnitine in mitochondria, prevention of metabolic inflexibility and disease initiation