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One common motif of plasticity of excitatory inputs to inhibitory neurons discussed in this review is that individual synapses are typically equipped with mechanisms, such as distinct sources of [Ca 2+ ] i rise and intracellular machinery, which can support multiple forms of plasticity

It is typically recommended for short-term use only, usually a few weeks to a few months

That multi-receptor approach is a major reason these drugs are more effective, said Kirk Habegger, Ph.D., professor in the Division of Endocrinology, Diabetes and Metabolism

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