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Never freeze reconstituted peptide solutionsice crystal formation physically disrupts peptide structure, leading to irreversible aggregation and loss of biological activity

In animal research, combined use shows improved results: Quicker formation of granulation tissue and wound closure Decreased edema and inflammation Better tendon-to-bone integration and ligament tensile load Systemic effects on the protection of distant organs, such as the liver and kidney in ischemia-reperfusion

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And direct injection does avoid any concern about absorption efficiency, since the peptide bypasses digestion and tissue barriers entirely