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Tesamorelin Dose for Cognition For cognition, studies have found success using the following dose of tesamorelin [14]: 1mg of tesamorelin One injection daily At night, 30 minutes before bed 5 days on, 2 days off Duration of 20 weeks How to Administer a Dose of Tesamorelin Clinical trials indicate that tesamorelin is injected subcutaneously, or under the skin