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Despite being only three amino acids, it carries the anti-inflammatory activity of the parent hormone

Specifically, changing the Val229 residue to alanine, selected in this study for further investigation, was predicted to trigger a change in the cavity and a buried exposure switch at the inactive receptor, thereby potentially modifying the interactions between itself and other pocket residues with cholesterol

[DOI] [Google Scholar] 272.Mitchell D.C., Knight C.A., Hockenberry J., Teplansky R., Hartman T.J

L-carnitine is a naturally occurring amino acid that plays an important role in the body's metabolism of fats