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Ltd., Beijing, China) used in this study are displayed in Table 1: including aquaporin 3 ( Aqp3 ), AQP4, Mucin-3, epithelial sodium channel beta ( Enac- ), Enac- , Claudin-1 , Occludin , tumor necrosis factor-alpha ( Tnf- ), interleukin-1beta ( Il-1 ), nod-like receptor pyrin domain containing 3 ( Nlrp3 ), Toll-like receptor 2 ( Tlr2 ), c-kit , stem cell factor ( Scf ), 5-hydroxytryptamine receptor 4 ( 5-Ht 4 r ), serotonin transporter ( Sert ) and Gapdh

However, not all agents in the class are equivalent

When Creatine reaches the muscles it is converted into Phosphocreatine, which is used to replenish the muscles energy reserves (ATP)