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243 The overexpression of VDR signaling can also maintain intestinal epithelial homeostasis and intestinal barrier function by upregulating claudin-2 and claudin-15

In June 2021, the FDA approved a higher-dose formulation of semaglutidemarketed under the brand name Wegovyspecifically for chronic weight management in adults with obesity or those who are overweight and have at least one weight-related health condition, such as type 2 diabetes, high blood pressure, or high cholesterol

We advise our patients to prioritize lean proteins, fiber, and whole foods and to avoid heavy, rich meals, especially in the beginning

Historically, centrally acting peptides were avoided due to concerns about neuropsychiatric side effects and bloodbrain barrier delivery