when do you start losing weight on semaglutide & Tirzepatide First Week on Semaglutide GLP-1:

Blancquaert L, Baguet A, Bex T, Volkaert A, Everaert I, Delanghe J, Petrovic M, Vervaet C, De Henauw S, Constantin-Teodosiu D, Greenhaff P, Derave W

Additional non-oral contraception is advised for 4 weeks after starting treatment and for 4 weeks after each dose increase If pancreatitis is suspected (severe, persistent abdominal pain with or without vomiting), stop Mounjaro immediately and seek urgent medical assessment Mounjaro is not indicated for type 1 diabetes or diabetic ketoacidosis The medication is not recommended during pregnancy or breastfeeding Patients should report any suspected side effects via the MHRA Yellow Card Scheme

So, a randomized controlled trial testing this dual efficacy is warranted. Still, this was an independent study that should allay earlier fears (eg, the FDA red flags) of increased suicidality with GLP-1 receptor agonists, he concluded

Reinforce defenses against everyday stressors