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With its demonstrated effectiveness, the medication has become a popular option, but the high cost remains a barrier for many

Because AOD 9604 is a research compound with no FDA-approved protocol and restricted compounding status, sourcing standards are particularly important for research consistency

However, a one-year randomized, double-blind, placebo-controlled trial in 253 elderly (65 years) adults with elevated homocysteine levels found that B vitamin supplementation (1,000 g/day of folate, 10 mg/day of vitamin B 6 , and 500 g/day of vitamin B 12 ) did not improve measures of cognitive function, including memory, despite lowering homocysteine levels (116)