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Deficiency of GSH, the major intracellular thiol, has been shown in human patients with acute pancreatitis, HIV infection, hyperthyroidism, Type I diabetes, and cirrhosis, 3-6 and has been associated with disease severity and decreased survival in some studies

MTHFR Gene Mutation Testing: Weighing the Benefits and Risks The MTHFR gene plays a crucial role in processing folate, a B vitamin essential for various bodily functions

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Because these polymorphisms have a high frequency, [60] they may have a substantial effect at the population level