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The body composition effects of the amylin analogs in humans are unknown but there is animal evidence that they spare lean mass

In writing about her own experience in using the medicine to help her shed 40 pounds, Washington Post columnist Ruth Marcus in June noted that Novo Nordisk mentioned the potential for weight loss in its ubiquitous cable ads (Oh-oh-oh, Ozempic!) The American Society of Health-System Pharmacists has reported shortages of semaglutide due to demand, leaving some people with diabetes struggling to find supply of the medicine

Sustained Weight Loss Both medications offer sustained weight loss, which can help individuals maintain their results over the long term

Though semaglutide may reduce systemic inflammation for some conditions, in rare cases, it might trigger localized joint discomfort