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Additionally, it markedly suppressed the expression of pro-inflammatory cytokines (TNF-, caspase-1, and NLRP3) and pro-fibrotic factors (fibronectin, -SMA, and collagen I) in the kidneys of mice

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Despite its advantages, its important to acknowledge GHK-Cus limitations when compared to traditional acne treatments in a research context: Limited Direct Evidence for Active Acne Vulgaris: While it has anti-inflammatory properties, there is currently limited direct clinical evidence specifically demonstrating GHK-Cu as a primary treatment for active acne breakouts (e.g., reducing papules, pustules, or cysts)

Some weeks may show little change, followed by periods of more noticeable progress