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1 Study design SELECT 1,4 : A multi-national, double-blind, placebo-controlled, event-driven CV outcomes trial of 17,604 adults with a BMI 27 kg/m and established CVD (prior MI, prior stroke, or PAD) assessing superiority of once-weekly Wegovy 2.4 mg vs placebo (1:1 randomization, with a 16-week dose escalation) for time to rst MACE