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Description

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PLC hydrolyzes the membrane phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) into two second messengers: inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG)

In order to collect a sufficient number of cells for implantation, isolated chondrocytes usually undergo an extensive expansion from 0.10.2 million to 4060 million (Huang et al., 2016)