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Healthcare workers, hospitality professionals, retail staff, and countless others operate on schedules that do not conform to the conventional weekend model, and these individuals need to think carefully about their unique circumstances when planning their start day

doi:10.1124/jpet.112.199497 PubMed: 23055539 Benoist CC, Kawas LH, Zhu M, et al

This lipotoxicity and oxidative stress vicious cycle creates a metabolic trap, which is particularly evident in glomerular mesangial cells and proximal tubular cells, thereby driving extracellular matrix deposition and the development of renal fibrosis