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The study included 100,455 people in the combination GLP-1RA and SGLT2i group and 339,540 people in the comparison SGLT2i group across 3 cohorts: T2D with atherosclerotic cardiovascular disease (ASCVD), T2D, and T2D with chronic kidney disease (CKD)

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Not all studies show a potential benefit, however, including a 2022 study that concluded Metformin did not significantly improve survival in breast cancer patients

[DOI] [PubMed] [Google Scholar] 81.Obeagu E.I., Obeagu G.U