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2024;208:107361 Braniste V, Al-Asmakh M, Kowal C, Anuar F, Abbaspour A, Tth M, et al

This paper demonstrates the advantages of direct reprogramming of ALS patient fibroblasts, via induced neural progenitor cells, into astrocytes, which are toxic to motor neurons in coculture and are non-clonal and retain the epigenetic features of ageing