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In addition, CB-839 has been extensively studied in hematological malignancies such as acute myeloid leukemia (AML) (Gregory et al., 2019), myelodysplastic syndrome (MDS) (Okabe et al., 2022), and multiple myeloma (MM) (Das et al., 2014)

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It is speculated that the interactions between LPAAT and other acyltransferases may disrupt the distribution of acyl groups on glycerol backbone (Chen et al

According to Robert Kushner, an obesity researcher at Northwestern University Feinberg School of Medicine , who led one of the STEP studies, semaglutide is a "game-changer" for people with obesity