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Endplate fractures compromise the disc immune privilege The intervertebral disc is an immune privileged organ, because it is secluded from immune surveillance

However, Vitamin B12 is an essential vitamin and requirements are increased during pregnancy

Vitamin B12 deficiency is one of the most common nutrient deficiencies in the world, especially for vegetarians, vegans and people with health conditions such as Crohns Disease or Celiac Disease which makes it hard to absorb nutrients

This might include the counteraction of various arrhythmias [66,67,68,69,70,71,72,73,74,75,76,77,78,80,81,82,102,103,105,106,122,123,154] and thromboses, even blood pressure disturbances (intracranial (superior sagittal sinus), portal and caval hypertension, and aortal hypotension [66,71,72,73,74,75,76,77,78,79,80,81,82], or hypertension (hyperkalemia, NOS-blockade) [67,105] that were attenuated/eliminated peripherally and centrally))