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For those with contraindications to, or personal preferences against, using pharmacologic therapies, the following natural supplements have evidence to support their use in managing perimenopausal symptoms: Phytoestrogens , found in soy, beans, flax seeds, and cruciferous vegetables, are plant compounds that may support the reduction of menopausal symptoms (5)

However, surgery also has some risks and complications, such as bleeding, infection, damage to the nearby nerves that control the voice box (laryngeal nerves) or the parathyroid glands that regulate calcium levels (hypoparathyroidism), and hypothyroidism

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According to preliminary results, ferroptosis may be involved in balancing the synovium growth and death